IRAK inhibitor 6 - Search Results

About 8 results found for searched term "IRAK inhibitor 6" (0.133 seconds)

Cat.No.	Name	Target
M20680	IRAK inhibitor 6	IRAK
	IRAK inhibitor 6 is a selective Interleukin-1 receptor-associated kinase 4(IRAK4) inhibitor with IC50 of 0.16 μM.
M27696	IRAK inhibitor 1	IRAK
	IRAK inhibitor 1 is a potent IRAK-4 inhibitor with IC50 of 216 nM, is poorly active against JNK-1 and JNK-2 with IC50 of 3.801 μM, and >10 μM, respectively.
M29213	GLPG2534	IRAK
	GLPG2534 is an orally active and selective IRAK4 inhibitor, with IC50 values of 6.4 nM and 3.5 nM for human and mouse IRAK4. GLPG2534 can be used for the research of inflammatory skin diseases.
M29236	GNE-2256	IRAK
	GNE-2256 (molecule 19) is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM).
M29657	IRAK4-IN-6	IRAK
	IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma.
M54868	BIO-7488	IRAK
	BIO7488
	BIO-7488 is a potent, selective, oral active and CNS-penetrant IRAK4 inhibitor, with IC50 values of 0.6 nM and >30 μM for IRAK4 and hERG, respectively.
M42004	IRAK4-IN-26	IRAK
	IRAK4-IN-26 is a IRAK4 inhibitor (IC50: 6.2 nM).
M54681	IRAK4-IN-21	IRAK
	IRAK4-IN-21 is an orally potent, selective, and potent IRAK4 inhibitor with IC50 values of 5 and 56 nM for IRAK4 and TAK1, respectively.IRAK4-IN-21 potently inhibits the production of IL-23 (IC50=0.17 µM) and may be useful in studies related to autoimmune diseases such as plaque psoriasis and psoriasis vulgaris. arthritis).